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One obvious possibility is that the same metabolic/hormonal abnormalities that characterize the diabetic condition in particular, elevated blood sugar, hyperinsulinemia and insulin resistance -- may also cause these complications and the associated chronic diseases

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Ongoing possible side effects may include nausea, diarrhea, vomiting, constipation, stomach (abdomen) pain, headache, tiredness (fatigue), upset stomach, dizziness, feeling bloated, belching, gas, stomach flu, heartburn, runny nose or, sore throat

Biomolecules 13(5):799 Manzanares W, Biestro A, Torre MH, Galusso F, Facchin G, Hardy G (2011) High-dose selenium reduces ventilator-associated pneumonia and illness severity in critically ill patients with systemic inflammation