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Previous reports have shown that RR has a protective effect against cardiac ischemia-reperfusion injury
Proc Natl Acad Sci 89:444448 Kolesnik B, Palten K, Schrammel A, Stessel H, Schmidt K, Mayer B, Gorren AC (2013) Efficient nitrosation of glutathione by nitric oxide
What varies is the manufacturing oversight, documentation standard, and supply chain traceability that determine confidence in compliance
This provides natural temporal separation without requiring strict clock-watching
Thus, subcellular compartmentalization has emerged as an important player in G protein functions
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