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GIP, like GLP-1, is an incretin hormone secreted by intestinal K cells in response to nutrient intake

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However, it is very important to have realistic expectations from the treatment

GLP-1 101/The 411 on GLP-1 GLP-1, Glucagon-like Peptide -1 , is a naturally occurring hormone made by enteroendocrine L-cells, hormone-producing cells in the lining of the ileum and colon (end of the small intestine and beginning of the large intestine)

Some clinicians report patients using it for extended periods without obvious problems