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Cleveland Clinic also explains that large or prolonged calorie deficits can reduce available energy and affect recovery, due to it being easier for the body to adjust to a smaller calorie deficit than a larger one

Because your appetite will be significantly reduced, it is crucial to focus on the quality of the food you consume

(2015) demonstrated that MOTS-c administration in mice led to improved metabolic profiles, including reduced weight gain and enhanced insulin sensitivity

The side effects we occasionally see in clinic are mild and typically transient