combining semaglutide and tirzepatide Tirzepatide: Evidence & Safety – PlexusDx What happens when you combine

Future of GLP-1 receptor agonists In a related editorial, Thiara noted that although Tang and colleagues found that GLP-1 receptor agonists and SGLT2 inhibitors had a similar effect on ADRD, the team did show that isolating semaglutide, the newest and most potent GLP-1 receptor agonist on the market, showed decreased risk of ADRD compared with SGLT2 inhibitors. Both studies had limitations, including short-term follow-up, low dementia event rates and confounding variables, Thiara wrote

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Both rely on the same active compound, though their intended applications differ significantly