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However, safety depends on: Following the recommended dosage Avoiding unnecessary overuse Consulting a healthcare professional if you have a medical condition Daily use should always be moderate and consistent, not excessive

10.1136/jnnp-2018-320106 63 GalimbertiD.VillaC.FenoglioC.SerpenteM.GhezziL.CioffiS

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But it gained widespread recognition after researchers realized that it binds to the melanocortin-1 receptor, triggering the production of melanin to increase pigmentation