No effects were seen on stool consistency, and adverse events were not different from placebo (i.e., constipation), except for nausea ( Unlike 5-HT 3 receptor antagonists, constipation was not reported as an adverse event in the trials assessing rifaximin
, which also circumvents the need for derivatization (Vera et al., 2020)
The scaffold domain provides the trimer interface, and the transport domain is used for binding amino acids and coupling ions
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