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The most frequently reported reactions are localized to the injection site and typically resolve within 24-48 hours

Once-daily subcutaneous (s.c.) injections of the potent NMDA receptor antagonist MK-801 in diet-induced obese (DIO) mice led to a dose-dependent decrease in food intake and body weight (Extended Data Fig

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This is substantially faster than the 2-3 weeks typically required for SSRIs to induce neurogenesis