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Bacteriostatic Water provides a suitable multi-use reconstitution vehicle for PEG MGF and the PEGylation of the MGF E-domain peptide provides aqueous solubility compatible with direct Bacteriostatic Water reconstitution without the acetic acid acidification sometimes required for unconjugated peptides

These additions include an accessory TMD called TMD0, a Lasso motif that connects TMD0 and TMD1, and a ~60 to 140 amino acid disordered domain termed the regulatory domain (R-domain) that connects NBD1 and TMD2 10,11,12,13

Expert Opin Investig Drugs 24:12871298 Ginn C, Khalili H, Lever R, Brocchini S (2014) PEGylation and its impact on the design of new protein-based medicines

Proteomics 18 , 233240 (2021)

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