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125 The expression and activity of the SOP enzymes appear to be strongly related to the H 2 S levels to which the corresponding cells or tissues are exposed

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Patients should immediately report any unexpected symptoms or changes in health to their healthcare provider to address potential adverse effects proactively

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Extracted data included title, trial name, the first author, publication year, country/region, dose, administration route, median follow-up time, sample size, age, sex, race, body mass index (BMI), smoke, blood pressure, glycated hemoglobin (HbA1c), T2DM duration, estimated glomerular filtration rate (eGFR), baseline CVD or CKD, and measures of effect assessed by the hazard ratio (HR) and its 95% confidence interval (CI) for each of the cardiovascular outcomes