metformin after semaglutide The maintenance of long-term weight loss withdrawal in obese women with PCOS treated with metformin: a 2-year observational study What next after metformin? A

This makes it particularly relevant during caloric restriction, when the body is more prone to catabolizing muscle tissue for energy

Stress management plays a role too

As all major obesity guidelines emphasize, lifestyle-based behavioral therapy remains the first-line foundation of care, with pharmacotherapy used as an adjunct rather than a replacement [35,36,37]

However, it is so important to talk to your doctor first, especially if you have any underlying medical conditions or take medications

GLP-1 agonists are a class of medications designed to mimic the action of a natural hormone called glucagon-like peptide 1