GLP-1 medications have been getting a lot of attention in recent yearsand for good reason
Some signs that you should extend your current dose period before escalating include diarrhea that occurs more than 3 times daily, diarrhea that has not improved after 3 weeks at the current dose, significant dehydration symptoms (dark urine, dizziness, dry mouth), or diarrhea that is interfering with daily activities or work
Brain insulin resistance is heavily implicated in the pathogenesis of Alzheimers disease, and takes part in amyloid-- and tau phosphorylation-mediated neuronal damage (Mullins et al., 2017)
You don't need a rigid diet plan, but food quality becomes more important because you're eating less total volume
Hsp90 also exerts a CaM-independent effect to promote eNOS activity (Takahashi and Mendelsohn, 2003)