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Novo Nordisks semaglutide and Eli Lillys tirzepatideboth leading GLP-1 agonists used for weight loss and diabetesare associated with a lowered likelihood of developing neurodegenerative disorders such as dementia, according to a recent study

Consistent with the renal benefits identified in our meta-analysis, SGLT2Is slowed eGFR decline versus placebo across both HF phenotypes in HFrEF (0.55 versus 2.28 ml/min/1.73 m per /year) and in HFpEF (1.25 versus 2.62 ml/min/1.73 m per year)

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The HbA1c cohort was composed of individuals with HbA1c values available in the dataset at baseline (between 120 and 1 days before the index date) and follow-up (between 540 and 719 days after the index date)