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Evidence Review GLP-1 receptor agonists are medications licensed in the UK for type 2 diabetes and obesity management

Given that sensory or gastrointestinal adverse effects, such as dysgeusia and persistent nausea, can impair nutritional intake and lead to early treatment discontinuation (particularly in vulnerable populations) future research must incorporate rigorous sensory testing, larger and more diverse cohorts, and adherence-related outcomes to clarify how incretin therapies influence taste perception and long-term eating behavior (153, 157, 161)

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When combined with insulin or sulfonylureas, dose adjustments may be needed to prevent hypoglycaemia

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