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Taher, A

High-dose supplementation (400 mg/day) of riboflavin over a time course of three months was found to significantly reduce the frequency, duration and pain score of migraine attacks in both men and women in a meta-analysis of eight RCTs and one intervention study 66

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Studies have shown that antidepressant treatment for patients with CHD and depression leads to substantial improvements in chest pain symptoms, depressive symptoms, and various cardiac parameters (109, 116, 117)

Quantitative real-time RT-PCR The RNA was extracted by TRIzol reagent (ThermoFisher Scientific) from cells treated or not with 200 M of PA during 24 h