glutathione lehyam L-Glutathione reduced (GSH) | Antioxidant Glutathione lahyam

AOP Development Strategy Context This AOP was developed for the project "CHRONIC TOXICITY OF PESTICIDES IN DRINKING WATER IN PARABA (TRIGGER): IDENTIFYING THE TRIGGERS OF A SILENT EPIDEMIC," financed by the "Fundao de Apoio Pesquisa do Estado da Paraba (FAPESQ-PB)." The project aims to understand how oxidative stress and reproductive toxicity can be triggered in animals by aquatic pollutants, such as atrazine Strategy The first step in developing this AOP was to conduct a literature review to gather toxicological data on the herbicide atrazine's impact on aquatic vertebrates in relation to oxidative stress and reproductive toxicity

Not suitable for pregnant/breastfeeding women, or individuals with kidney, liver, or active infection conditions

The way she listens and understands problems is remarkable, something not everyone can do

Mattson MP, Shea TB

While IGF-1 has important physiological functions, elevated levels carry potential concerns including increased cell proliferation that may support tumor growth in individuals with cancer or pre-cancerous conditions, accelerated aging processes through growth pathway activation, potential cardiovascular effects with chronic elevation, and metabolic consequences including effects on glucose and lipid metabolism