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Total regain averages 50-70% of lost weight by 12 months if lifestyle changes made during treatment are not maintained

Hypoglycemia in type 2 diabetic patients randomized to and maintained on monotherapy with diet, sulfonylurea, metformin, or insulin for 6 years from diagnosis: UKPDS73

International Journal of Preventive Medicine, 11 , Article 132

Weeks 5-8: Optimization and Response Assessment The second month represents an optimization phase where protocols may be adjusted based on individual response and tolerance

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