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The review maps engineering solutions to tissue-specific delivery challenges, critically appraises evidence across primary musculoskeletal indications, and identifies translational bottlenecks separating preclinical claims from clinical reality

doi: 10.1523/JNEUROSCI.2939-14.2015 53 ChoiG

Notably, there are additional studies that need to be addressed prior to initiating preclinical development, including assessments of potential immunogenicity, molecular size, pharmacokinetics/pharmacodynamics (PK/PD), and the presence of an unpaired cysteine

Powerful yet gentle, it is designed for sensitive skin but works for all skin types