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The first is DF, a carbohydrate polymer derived from bacterial cell walls that cannot be hydrolyzed by enzymes in the small intestine, which exerts complementary or overlapping functions with prebiotics

Luli, M

26,27 Clinical trials (e.g., NCT04916236) are currently underway to explore the potential of this approach for patients

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Remarkably, this proinflammatory ATM polarization phenotype was also observed in PAR2-R38E when compared with PAR2-WT mice (Figure 4B and Supplemental Figure 6B)