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Although there are various causes for sleep disorders including medical conditions such as respiratory disorders, diabetes, pain, anxiety, and depression, the most fundamental cause of sleep disorders is stress [17, 18]

Acknowledgments We thank all participants and their families for supporting this study

The third option must be coordinated with the neurosurgical service to ensure that the pump catheter system functions properly afterwards

Meaningful immune rebalancing typically requires 3-6 months Tissue repair (TB-500, BPC-157): Varies by tissue type and damage extent, typically 4-12 weeks for meaningful structural improvement Set realistic expectations

doi: 10.1016/j.pnpbp.2018.05.005