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Research on AD models has suggested that reactive astrocytes are more susceptible to neuronal reprogramming than their nonreactive counterparts, underscoring the role of astrocytic heterogeneity in influencing cell differentiation 25,149

Vitamin B12 may reduce the effectiveness of some chemotherapy drugs, such as methotrexate or 5-fluorouracil, and may also be impacted by medications like metformin, proton pump inhibitors (PPIs), and certain antibiotics (e.g., chloramphenicol)

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Understanding the mortality burden of the obesity epidemic Association between BMI and all-cause mortality among never-smokers by age This age-stratified analysis suggests that the relationship between higher BMI and all-cause mortality is attenuated by age