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The recommended dosing of IV acetaminophen for adults or children weighing more than 50 kg is 650 milligrams every 4 hours or 1000 milligrams every 6 hours, with a maximum total daily dose of 4 grams

[PUBMED Abstract] Larkin J, Ascierto PA, Drno B, et al.: Combined vemurafenib and cobimetinib in BRAF-mutated melanoma