& Bardor, M
Compared to the group with normal renal function, the mean exposure of semaglutide appeared to be higher in the group with mild renal impairment (estimated ratio: AUC 24,Day10 1.37 [90% CI 0.912.06] and C max,Day10 1.39 [0.932.06]), whereas lower exposure was observed in the group with severe renal impairment (estimated ratio: AUC 24,Day10 0.61 [90% CI 0.420.88] and C max,Day10 0.61 [0.420.87])
Case 1 A 77-year-old male with a history of obesity, prediabetes, coronary artery disease, hyperlipidemia, stage 3a chronic kidney disease, chronic compensated heart failure with reduced ejection fraction, history of lumbar decompression (2017), and left total knee arthroplasty (2012) presented in September 2023 with onset of left foot drop and again in October 2023 with development of foot drop on the right as well
Dose adjustment of Qtencare Tablet may be needed
Patients receiving reconstituted peptide vials should store them refrigerated and discard by the beyond-use date printed on the label
