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A previous drug blocking the receptor, known as rimonabant, had led to depression, anxiety and even suicidal thoughts, and was thus withdrawn from the market after less than three years

Participants received weekly subcutaneous injections with standard dose escalation protocols to minimize gastrointestinal side effects

Another feature setting retatrutide apart is how it improves heart and kidney health

The long-term data on standard-dose GLP-1 medications continues to be reassuring most cardiovascular and renal outcome trials now extend out 3 to 5 years

Frequently Asked Questions Why does retatrutide cause sulphur burps