Clinically BPH is manifested as lower urinary tract symptoms (LUTS) and consisting of voiding and storage symptoms such as slow urinary stream, splitting or spraying of urinary stream, recurrent urinary stream, straining to void and terminal dribbling, hesitancy, urgency, increased frequency, and incontinence
Through a number of mechanisms of action connected to the homeostatic preservation of the hypothalamicpituitary-adrenal (HPA) axis and the regulation of important mediators of the stress response, ashwagandha is regarded as an adaptogen that aids in the restoration of homeostasis by counteracting external stimuli as nonspecific regulators [158]
Interestingly, the application of low-magnitude compressive stress (0.03 kPa) on weakly adhesive MDA-MB-231 breast cancer cells decreases their motility, highlighting the critical role of cell-matrix interactions in stress-dependent cell responses [122]
Sam Rhee: Agreed
Our experience shows that its localized effects are where it truly shines, acting as a sort of on-site foreman for cellular repair crews
