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Accordingly, the new customised C-terminal ELISA revealed preserved GLP-1 immunoreactivity in the in vitro experiments and secretory profiles of GLP-1 in vivo, which, unlike those obtained with the sandwich ELISAs, correlated to those of glucose absorption (blood glucose), GIP and insulin in a physiologically meaningful manner

The compound's effects extend to muscle tissue, where NNMT inhibition modulates cellular energetics and contractile function

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Results A significant decrease in T3 and T4 levels and serum reduced glutathione in the group II when compared with the other groups

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