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Mounjaro is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

Vitamin K2 was shown to inhibit NF-B signaling and the production of proinflammatory cytokines, such as IL-1 and IL-6

[48] Consistent evidences suggest that GLP-1RAs have anti-inflammatory properties that may modulate the immune-system

Monitor blood glucose levels

These comparator categories were prespecified to keep comparisons clinically meaningful and to avoid pooling different control types that could blur ALCs added effect