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This multi-receptor mechanism distinguishes retatrutide from earlier generations of incretin-based research compounds including GLP-1 mono-agonists such as semaglutide, and dual GIP/GLP-1 agonists such as tirzepatide by introducing glucagon receptor activation as an additional metabolic axis

Back Habener, JF (2024) 'Acknowledgements' 2024 Lasker-DeBaley Clinical Medical Research Award

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Born in Canada, Bell received his BSc in Zoology and MSc degree in Biology from the University of Calgary and his PhD in Biochemistry from the University of California, San Francisco