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Quick Answer: Retatrutide vs Tirzepatide Retatrutide is a triple agonist (GLP-1 + GIP + glucagon) that achieved 24.2% weight loss in 48-week trials

And it's preventable

Parents should watch for: Mood swings Withdrawal Big changes in sleep or appetite Teens need a care team that includes a doctor, mental health provider, and family support

Digestive issues Difficulty in moving to maintenance or transitioning off the medications Not knowing what to eat to maximize the benefits of the medications Other challenges include slower metabolism, difficulty keeping weight off, and side effects that might make sticking with the medication harder

They've also often lost confidence in the idea that anything will work, which affects how they engage with later treatment