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Important distinction: actual GLP-1 medications (Ozempic, Wegovy, Zepbound, Mounjaro) are FDA-approved engineered hormone analogs delivered by injection, with efficacy established through large, independently published clinical trials

How Does GLP-1 work and Who Could Benefit

Progress can look different from person to person

Coordinated action is required to ensure that people with type 2 diabetes, cardiovascular disease, heart failure, or chronic kidney disease are treated appropriately with an SGLT-2 inhibitor or GLP-1RA

Semaglutide 0.25 mg to 0.5 mg (Ozempic starter range) is roughly equivalent to tirzepatide 2.5 mg in terms of introductory level of GLP-1 activity