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In addition, changes in respiratory quotient pointed out greater fat oxidation after multi-agonist treatments, which may contribute to the beneficial effects of the compounds in the metabolic handling of PWA mice

Eat small, bland meals if nausea occurs

JWU-A021 activates TRPA1 channels to promote Ca 2+ influx We next sought to identify the molecular target that mediates the action of JWU-A021 to stimulate an increase of [Ca 2+ ] i in STC-1 cells