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[4] [5] The three primary subcutaneous injection sites used for comparable licensed therapies (such as semaglutide and tirzepatide, as described in their UK Summary of Product Characteristics) are: Abdomen the area around the stomach, avoiding the area immediately around the navel Front (anterolateral) thigh the outer-front portion of the upper thigh Upper arms the outer area of the upper arm, typically requiring assistance from another person for self-administration The abdomen is generally considered the most accessible and commonly used site, as it offers a relatively large surface area of subcutaneous fat and is straightforward to self-administer

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The cost of GLP-1 medications can be high, often ranging from $500 to $1,000 per month

This additional impact on body weight is one reason physicians may titrate patients up to 3.0 mg or 4.5 mg when blood-sugar control and weight loss are treatment goals

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