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Real patients, real transformations

GIP receptor activation Glucose-dependent insulinotropic polypeptide (GIP) is the second receptor target, similar to tirzepatide (Mounjaro, Zepbound): Effects: Enhances insulin release from the pancreas Works synergistically with GLP-1 for appetite control May influence fat storage and energy balance Improves glucose regulation Tirzepatide's success as a dual GLP-1/GIP agonist demonstrated that adding GIP to GLP-1 enhances weight loss beyond GLP-1 alone

The UK Summary of Product Characteristics states that liraglutide is not recommended in patients with inflammatory bowel disease due to limited study data and potential gastrointestinal adverse effects

Hospital readmission and emergency department revisits of homeless patients treated at homeless-serving hospitals in the USA: observational study

doi: 10.1038/nbt950