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Eligible studies were cohort or case-control studies that assessed maternal exposure to GLP-1 receptor agonists from 90 days before conception through the end of pregnancy and included an appropriate unexposed comparator group

The nuclei of the hepatocytes were visible as dark red structures within the cells, whereas the cytoplasm was stained red

They are generating mice in which the protein SPHKAP can be specifically deleted from -cells, allowing them to examine how disrupting this signalling hub affects pancreatic function and GLP-1R signalling

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