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Some transition metals including iron, chromium, lead, and cadmium generate lipid peroxidation e : fatty acids, cod liver oil, biological membranes, tissues and organs, suggesting that metals contribute to the oxidative effects of lipid peroxidation observed in various diseases (Repetto et al., 2010a

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Even when the main compound patent expires, generic competitors must navigate a growing web of patents, making litigation and the delay of any market entry almost inevitable

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