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1ak), and the fact that the conjugate fails to affect body weight and glycaemia in the GLP-1R knockout mice (Fig

(PDF) Duda, J.M.*, Moser, A.D.* Ironside, M., Null, K.E., Holsen, L.M., Zuo, C.S., Du, F., Esfand, S.M., Chen, X., Perlo, S., Richards, C.E., Lobien, R., Alexander, M., Misra, M., Goldstein, J.M.#, Pizzagalli, D.A.# (2024)

Melatonin further reinforces insulin sensitivity by synchronizing circadian insulin secretion, improving mitochondrial efficiency in hepatocytes and skeletal muscle, and attenuating the nocturnal cortisol overshoot typical in PCOS (226, 227)

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