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The timing hypothesis now established in the literature suggests that initiating HRT before age 60 or within 10 years of menopause is associated with a substantially more favorable risk profile and, in some analyses, active cardiovascular benefit

Weight loss was a big part of my goal

While it is not yet approved for general use, access through prescription referral services is available for those who qualify

When it hits: Often worse in the morning (after overnight electrolyte losses) and after exercise (when sweating accelerates depletion)

Role of lifestyle and glucagon-like peptide-1 receptor agonists for weight loss in obesity, type 2 diabetes and steatotic liver diseases