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[1] Dose-escalation studies, such as a 12-week trial on gradual titration, revealed that beginning at lower doses (e.g., 4 mg) and slowly increasing to therapeutic levels significantly reduced the incidence of nausea, vomiting, and diarrhoea

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Kynureninase is a pyridoxal phosphate (vitamin B6)-requiring enzyme encoded by the KNYU gene

RML/RARA, a fusion protein in acute promyelocytic leukemia, prevents growth factor withdrawal-induced apoptosis in TF-1 cells

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