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But in practice the scientists had to test out a number of different linker molecules, and chemically modify the GLP-1 structure slightly, in order to get the new drug to work

The study of Sai et al

Patients no longer need to wait months for an in-person appointment, battle insurance denials, or navigate confusing pharmacy chains

You may notice some minor stomach aches, like nausea, burping, gas, or constipation

Because coinsurance amounts are pegged to the list price, Medicare beneficiaries required to pay coinsurance could face monthly costs of $325 to $430 before they reach the new cap on annual out-of-pocket drug spending established by the Inflation Reduction Act around $3,300 in 2024, based on brand drugs only, and $2,000 in 2025