Am J Physiol Endocrinol Metab 2004, 287(2): E199-206
For context, the Phase 2 NEJM result at 24 weeks was 17.5% at the same 12 mg dose
Unlike natural GLP-1, which breaks down in 1-2 minutes, the modified peptide has a longer half-life, ranging from hours to days
You may need to avoid weight loss medications if you: Have a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2 (MEN2) Have a personal or family history of pancreatitis or gallbladder disease Are allergic to any of the ingredients in the medication Are pregnant or breastfeeding Have a history of eating disorders, substance abuse, addiction , or certain mental health conditions If youre interested in weight loss medications, talk to your healthcare provider
The best next step is a consultation so we can assess whether your laxity is mild, moderate, or surgical-level, and then map out a realistic plan using the right combination of tightening, collagen stimulation, skin hydration, resurfacing, and skincare