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Histotripsy is a non-invasive, non-thermal, mechanical process that uses a focused beam of sonic energy to destroy cancerous liver tumors and is currently in a non-randomized, prospective clinical trial to evaluate the efficacy and safety of the device for the treatment of primary or metastatic tumors located in the liver

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Invariant natural killer T (iNKT) cells, which share features of both NK and T cell lineages, also contribute to intestinal immunoregulation