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It stimulates tissue repair at the cellular level

IM bioavailability: 14-19% (rats) vs 45-51% (dogs): human figure unknown

As a preventive treatment, Botox not only helps reduce the physical symptoms but also contributes to an improved mental state, as many individuals experience reduced stress and anxiety related to the unpredictability of their migraines

The reason researchers combine the two is pathway complementarity

The takeaway, she said, is that your doctor may need to adjust your medications to keep you safe, and these drug interactions are a recurring theme in safety reviews like this one in the British Journal of Clinical Pharmacology