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However, whilst the IGF-1R is capable of signal transduction, the IGF-2R is not and binding results in lysosomal degradation of IGF-2

Chandel, Northwestern University) 24 and Ndufs2 loxP/loxP (J

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Excluding one participant with ASD who did not fast on the day of the MRS scan did not materially alter the results (please note that neurometabolite measures in the thalamus of this participant were already excluded by our quality check)