Antioxidants such as Vitamins A, C, and E provide radiation protection because radiation damage mimics oxidative stress associated with active oxygen toxicity.[] Tocopherol monoglucoside, a water-soluble Vitamin E derivative, has been found to be very effective in protecting DNA after oral or intraperitoneal administration of DNA against in vitro as well as gamma radiation.[] Melatonin (N-acetyl-5-methoxytryptamine), a pineal hormone that plays a role in the regulation of the neuroendocrine axis, is a highly effective free radical scavenger and antioxidant.[] When administered to mice before exposure to radiation, melatonin offered significant radiation protection, which is assessed by the frequency of chromosomal abnormalities in bone marrow cells, spermatogonia, spermatocytes and micronuclei.[] This study was performed to evaluate oxidative status, DNA damage and histopathological changes of radiation-induced lung injury
Periodic adjustments of insulin may also be necessary during maintenance as guided by glucose and HbA1c levels
Available at: Mouser JF, Hak EB, Helms RA, et al
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