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Retatrutide may be appropriate for patients with significant obesity, particularly those who have plateaued on GLP-1 or dual-agonist therapies, or those with concurrent metabolic concerns such as elevated liver fat or poor lipid profiles

Wegovys introductory list price was over $1,300, making these drugs financially inaccessible for many people in these communities

Some patient assistance programs are there too

26 Subjects were administered 0.75 mg of liraglutide as a single dose, and evaluated after a 72-hour period to determine if hepatic impairment influenced liraglutides pharmacokinetic and safety profile

83.5% of Wegovy patients lost greater than or equal to 12 lbs , with 2 out of 3 patients losing an average of 23 lbs, and 30% losing more than 45 lbs