Interestingly, levels of oxidized nucleic acids in mtDNA are reported to be significantly elevated in preclinical AD, again stressing mitochondrial abnormalities as an early event of AD progression (Wang W
Multiple studies suggest supplemental ALCAR improves cognitive function and energy levels, delays onset and improves symptoms of dementia and Alzheimers, improves feelings of depression (especially in the elderly) and may provide benefits for Downs syndrome, Parkinsons, stroke and other neurological disorders, along with many other conditions
Large doses can also increase the likelihood of oxalate stones in the urinary tract in patients with a history of nephrolithiasis, hyperoxaluria, or oxalosis
J.MiarroJ.ContrerasC.Soto-MndezF.et al (2020)
This isn't a pharmacological side effect of AHK-Cu so much as a handling consideration, but it belongs in an honest safety picture because community AHK-Cu use is almost entirely self-prepared