Moreover, while some studies report improvements in performance metrics such as endurance and grip strength, others do not find significant differences in VO max, body composition, or performance time
Drugs investigated across these studies include: Liraglutide ( n = 1, LEADER [12])
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The addition of semaglutide also provides weight loss benefits averaging 5% to 10% of body weight, which metformin typically does not deliver
Furthermore, the endothelin system has been implicated in the deposition of collagen and fibrosis (45)