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Six weeks of GLP-1 infusion resulted in significant improvements in fasting (decrease of 4.3 mM glucose) and 8 h mean glucose (decrease of 5.5 mM), fasting and mean 8h free fatty acids, a reduction in HbA1c from 9.2% to 7.9%, a decrease in fructosamine from 349 uM to 282 uM, and a reduction in gastric emptying 3,4

Most people notice appetite changes within the first 2 to 4 weeks, even at the 0.25 mg initiation dose

Gum Recession: Some patients report gum sensitivity and recession, which can expose tooth roots

Morphological studies demonstrated a particularly high density of GLP-1R expression in the PVN of mice (Merchenthaler et al., 1999

2022 Feb;179(4):62541