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Figure 4 Figure 5 The Ferroptosis Inducer RSL3 Suppresses CRC Regrowth After 5-FU Therapy Cessation In Vivo To confirm the anti-tumor regrowth effect of GPX4 inhibition after the removal of anti-colorectal cancer agents, we used a subcutaneous tumor mouse model

Mitochondrial ROS production usually occurs in the early stage of cell injury, which can lead to destruction of the cell membrane of the alveolar epithelial cells and inactivation of surfactant, thus increasing membrane permeability, leading to increased leakage of proteins into the alveoli during lung injury (Alwazeer et al., 2021)

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