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For example, rat TDSCs treated with IGF-1 (1, 10, and 100 ng/mL) for 28 days exhibited the increased expression of tendon-specific marker (SCX) and significantly decreased expression of chondrogenic and osteogenic marker (collagen type II) ( in vitro culture with significant upregulation of tenocytic markers (SCX, collagen type III, and decorin) ( in vivo data are available regarding the efficacy of exogenously delivery of IGF-1 in combination with stem cells to treat tendon injury
[7] As a result, MB is contraindicated in patients with known G6PD deficiency, and screening for this enzyme deficiency is recommended when considering MB therapy, especially in populations where G6PD deficiency is more prevalent
Figure 1, Panel A and Figure 1, Panel B show the steady state for a male and a female, respectively
doi: 10.3177/jnsv.58.287
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